Toll-like receptor 4 mediates endothelial cell activation through NF-κB but is not associated with endothelial dysfunction in patients with rheumatoid arthritis

Articolo

Data di Pubblicazione:

2014

Citazione:

Menghini, R., Campia, U., Tesauro, M., Marino, A., Rovella, V., Rodia, G., Schinzari, F., Tolusso, B., Di Daniele, N., Federici, M., Zoli, A., Ferraccioli, G., Cardillo, C., Toll-like receptor 4 mediates endothelial cell activation through NF-κB but is not associated with endothelial dysfunction in patients with rheumatoid arthritis, <>, 2014; 9 (6): e99053-e99053. [doi:10.1371/journal.pone.0099053] [http://hdl.handle.net/10807/64375]

Abstract:

To investigate the effects of TLR4 antagonism on human endothelial cells activation and cytokine expression, and whether the Asp299Gly TLR4 polymorphism is associated with better endothelial function in patients with rheumatoid arthritis (RA).

Tipologia CRIS:

Articolo in rivista, Nota a sentenza

Keywords:

Aorta; Arthritis, Rheumatoid; Cells, Cultured; Disaccharides; Endothelium, Vascular; Humans; Lipopolysaccharides; NF-kappa B; Phosphorylation; Sugar Phosphates; Toll-Like Receptor 4

Elenco autori: