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Pediatric Bell's Palsy: Prognostic Factors, Management Strategy, and Treatment Outcomes

Articolo
Data di Pubblicazione:
2024
Citazione:
Di Sarno, L., Caroselli, A., Graglia, B., Causio, F. A., Gatto, A., Pansini, V., Di Vizio, N. C., Chiaretti, A., Pediatric Bell's Palsy: Prognostic Factors, Management Strategy, and Treatment Outcomes, <>, 2024; 14 (1): N/A-N/A. [doi:10.3390/jcm14010079] [https://hdl.handle.net/10807/303497]
Abstract:
Background/Objectives: Bell's palsy (BP) is a neurological disorder characterized by sudden unilateral peripheral facial paralysis. The etiology in children remains largely unknown, and standardized management strategies are lacking. The aim of this retrospective cohort study is to evaluate clinical features, laboratory markers, and therapeutic options associated with recovery to identify potential prognostic factors and validate therapeutic strategies, with a particular focus on the role of corticosteroids and vitamin supplementation. Methods: A retrospective cohort study was conducted on 88 children (aged < 18 years) diagnosed with BP at a single tertiary care center between 2010 and 2023. Clinical data, including House-Brackmann (HB) scores, were collected at baseline and at a two-month follow-up. Statistical analysis was performed to assess the associations between demographic, clinical, and laboratory parameters with recovery outcomes. Prednisone and vitamin supplementation were administered at the discretion of the treating pediatrician. Results: In total, 81.8% of patients achieved complete recovery at 2-month follow-up (HB grade 1). No significant associations were found between recovery and gender, age, side of paralysis, initial HB grade, or laboratory markers. However, the use of prednisone was associated with a higher rate of incomplete recovery (p = 0.024), with higher doses correlating with poorer outcomes (p = 0.022). Vitamin supplementation showed no significant impact. Conclusions: Our findings suggest that corticosteroid therapy may not be a disease-modifying factor that ultimately influences outcomes in pediatric BP. Further large-scale studies are needed to define evidence-based protocols for managing pediatric BP.
Tipologia CRIS:
Articolo in rivista, Nota a sentenza
Keywords:
Bell’s palsy; House–Brackmann; children; facial nerve; prognosis; steroids
Elenco autori:
Di Sarno, Lorenzo; Caroselli, Anya; Graglia, Benedetta; Causio, Francesco Andrea; Gatto, Antonio; Pansini, Valeria; Di Vizio, Natalia Camilla; Chiaretti, Antonio
Link alla scheda completa:
https://publicatt.unicatt.it/handle/10807/303497
Link al Full Text:
https://publicatt.unicatt.it//retrieve/handle/10807/303497/707140/jcm-14-00079.pdf
Pubblicato in:
JOURNAL OF CLINICAL MEDICINE
Journal
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Settori (3)


LS7_3 - Other medical technologies for diagnosis and monitoring of diseases - (2020)

Settore MED/38 - PEDIATRIA GENERALE E SPECIALISTICA

Settore MEDS-20/A - Pediatria generale e specialistica
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