Low-dose radiotherapy as a chemo-potentiator of a chemotherapy regimen with pemetrexed for recurrent non-small-cell lung cancer: a prospective phase II study

Academic Article

Publication Date:

2012

Short description:

Mantini, G., Valentini, V., Meduri, B., Margaritora, S., Balducci, M., Micciché, F., Nardone, L., De Rose, F., Cesario, A., Larici, A. R., Maggi, F., Calcagni, M. L., Granone, P., Low-dose radiotherapy as a chemo-potentiator of a chemotherapy regimen with pemetrexed for recurrent non-small-cell lung cancer: a prospective phase II study, <>, 2012; 105 (2): 161-166. [doi:10.1016/j.radonc.2012.09.006] [http://hdl.handle.net/10807/39779]

abstract:

Low-dose radiotherapy (LDR) (<50 cGy) induces enhanced cell killing in vitro via the hyper-radiation sensitivity phenomenon. Aim of this study was to evaluate the safety and efficacy of a palliative regimen combining pemetrexed and LDR (as a chemopotentiator) on patients affected by recurrent non-small-cell lung cancer (NSCLC).

Iris type:

Articolo in rivista, Nota a sentenza

Keywords:

nsclc

List of contributors: